01 - In a large bowl, gently combine ground beef with smoked paprika, garlic powder, onion powder, salt, black pepper, cayenne pepper, and Worcestershire sauce. Divide into 8 equal portions and shape into patties approximately 0.5 inch thick.
02 - Whisk together mayonnaise, Sriracha, and lime juice in a small bowl until fully incorporated. Reserve for assembly.
03 - Heat a grill pan or cast-iron skillet over medium-high heat. Cook beef patties 3-4 minutes per side to desired doneness. During the final minute, top each patty with pepper jack cheese and cover to facilitate melting.
04 - Melt butter in a separate skillet over medium heat. Toast slider buns cut side down until light golden brown, approximately 1-2 minutes.
05 - Spread spicy mayo on both cut surfaces of each bun. Layer on bottom bun: lettuce leaf, beef patty with melted cheese, jalapeño slices, red onion. Crown with top bun.
06 - Transfer prepared sliders to serving platter and serve immediately while patties and buns retain optimal temperature.